Attract

P-15 facilitates and expedites ingrowth of bone by promoting the immigration of reparative cells from the surrounding tissues.

Attract

i-FACTOR Bone Graft is based on the biological activity of the synthetically derived 15-amino acid peptide found naturally in Type I human collagen. This 15-amino acid peptide (P-15) is responsible for the attachment and proliferation of osteogenic cells. These cells have an affinity for and attach to the P-15 found in i-FACTOR Bone Graft in a similar way they would naturally with Type I collagen in bone

i-FACTOR increases the opportunity for cell binding in the fusion site by making an abundance of P-15 available to osteogenic cells. The ability of P-15 to enhance cell binding hastens the process of new bone formation and closely resembles the natural process of bone regeneration. Once cells attach, to the P-15 immobilised on the ABM substrate, the cascade of events leading to new bone formation commences.

IDE Study

i-FACTOR Bone Graft shown to be superior to autograft based on analysis of patient response to all four clinical endpoints from the pivotal IDE trial.

Find out more