A Powerful Cell Attachment Factor Backed by Level 1 Human Clinical Data

Learn more about i-FACTOR Find your Distributor

i-FACTOR Peptide Enhanced Bone Graft is a drug/device combination that creates a new category of bone graft technology.

Take a moment to review our introduction to i-FACTOR, our Level-1 IDE study and comparative performance sections given below.

Introducing i-FACTOR

Introducing i-FACTOR

i-FACTOR Peptide Enhanced Bone Graft is the only biologic bone graft that uses a unique small peptide attachment factor (P15 Osteogenic Cell Binding Peptide) bound to anorganic bone mineral (ABM). 

Learn more
Comparative performance

Comparative Performance

In the lecture video presentation “Bone Grafting Options & Evidence” Company President Jeff Marx, Ph.D. analyzes the market for bone void fillers and bone graft substitutes.

Learn more
IDE Study

IDE Study

i-FACTOR Peptide Enhanced Bone Graft has shown to be superior to autograft based on analysis of patient response to all four clinical endpoints from the pivotal IDE trial.

Learn more

A New Category of Bone Graft

i-FACTOR is making a difference in the lives of patients around the world. As surgeons weigh up the evidence they come to a conclusion that i-FACTOR is a bone graft that gives them the clinical evidence they required and the safety they demand.

Watch our surgeon video testimonials

Mechanism of action of i-FACTOR

i-FACTOR Biologic Bone Graft novel mechanism of action enhances the body’s natural bone healing process, resulting in safe, predictable bone formation. ABM/P-15 has been in human clinical use for more than 17 years in an estimated 500,000 patients worldwide.

Learn more about the science

Evidence

Mechanism of action

Key to choosing the appropriate graft material is an understanding of how it works. Learn more about the natural process and what to expect from i-FACTOR Bone Graft.

View evidence

Pre clinical

Studies have shown that P-15, in combination with ABM, mimics the behavior of autograft bone. Learn more about the depth of scientific research supporting this novel bone graft.

View evidence

Clinical

Research needs to translate into patient outcomes. Learn more about how i-FACTOR is transforming patients’ lives by providing clinicians with Level-1 data demonstrating the safety and efficacy of this new category of bone graft.

View evidence