The First Bone Graft with P-15 Osteogenic Cell Binding Peptide

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i-FACTOR Peptide Enhanced Bone Graft is a drug/device combination that creates a new category of bone graft technology.

Take a moment to review our introduction to i-FACTOR, our Level-1 IDE study and comparative performance sections given below.

Introducing i-FACTOR

Introducing i-FACTOR

i-FACTOR Peptide Enhanced Bone Graft is the only biologic bone graft that uses a unique small peptide attachment factor (P15 Osteogenic Cell Binding Peptide) bound to anorganic bone mineral (ABM). 

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Comparative performance

Comparative Performance

In the lecture video presentation “Bone Grafting Options & Evidence” Company President Jeff Marx, Ph.D. analyzes the market for bone void fillers and bone graft substitutes.

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IDE Study

IDE Study

i-FACTOR Peptide Enhanced Bone Graft has shown to be superior to autograft based on analysis of patient response to all four clinical endpoints from the pivotal IDE trial.

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A New Category of Bone Graft

i-FACTOR is making a difference in the lives of patients around the world. As surgeons weigh up the evidence they come to a conclusion that i-FACTOR is a bone graft that gives them the clinical evidence they required and the safety they demand.

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Mechanism of action of i-FACTOR

i-FACTOR Biologic Bone Graft novel mechanism of action enhances the body’s natural bone healing process, resulting in safe, predictable bone formation. ABM/P-15 has been in human clinical use for more than 17 years in an estimated 500,000 patients worldwide.

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Evidence

Mechanism of action

Key to choosing the appropriate graft material is an understanding of how it works. Learn more about the natural process and what to expect from i-FACTOR Bone Graft.

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Pre clinical

Studies have shown that P-15, in combination with ABM, mimics the behavior of autograft bone. Learn more about the depth of scientific research supporting this novel bone graft.

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Clinical

Research needs to translate into patient outcomes. Learn more about how i-FACTOR is transforming patients’ lives by providing clinicians with Level-1 data demonstrating the safety and efficacy of this new category of bone graft.

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