i-FACTOR and P-15

i-FACTOR Bone Graft is an advanced biologic that is supported with level I evidence, satisfies the highest regulatory imperatives, and provides a better cost/benefit ratio than engineered growth factors and cellular allografts.

i-FACTOR Bone Graft is the only biologic bone graft made of a small peptide, P-15 Osteogenic Cell Binding Peptide, bound to an anorganic bone mineral (ABM). This unique combination creates a surface-bound “Attract, Attach, Activate” mechanism of action that enhances the body’s natural bone healing process. Being surface-bound, all cellular activity resulting from P-15 Osteogenic Cell Binding Peptide attachment is restricted to the implant surface so bone cannot grow where it doesn’t belong (ectopic bone growth).

i-FACTOR Bone Graft is not a morphogen so, unlike engineered growth factors, the signals sent following P-15 Osteogenic Cell Binding Peptide attachment in a bony site only activate cells that are pre-programmed to become osteoblasts.

i-FACTOR Bone Graft products are sterilized after packaging (terminally sterilized), can be stored at room temperature and have a three-year shelf life. i-FACTOR Bone Graft is ready to use and thus requires no mixing or other preparation prior to use.

For important U.S. safety and risk information, click here and see contraindications, warnings, precautions, and potential adverse events sections.