Mechanism of Action
Key to choosing the appropriate graft material is an understanding of how it works. Learn more about the natural process and what to expect from i-FACTOR Bone Graft.
View evidence
Research needs to translate into patient outcomes. Learn more about how i-FACTOR is transforming patients’ lives by providing clinicians with Level-1 data demonstrating the safety and efficacy of this new category of bone graft
Arnold PM, Sasso RC, Janssen ME, Fehlings MG, Smucker JD, Vaccaro AR, Heary RF, Patel AI, Goulet B, Kalfas IH, Kopjar B. i-Factor™ Bone Graft versus Autograft in Anterior Cervical Discectomy and Fusion. Results of the Prospective Randomized Single-blinded Food and Drug Administration Investigational Device Exemption Study. Spine. 2016; 41 (13): 1075–1083.
View our evidence & publications
Preclinical
Studies have shown that P-15, in combination with ABM, mimics the behavior of autograft bone. Learn more about the depth of scientific research supporting this novel bone graft.
View evidenceThe proof you require, the safety you demand.
Clinical Superiority
Level 1 data supports your evidence based clinical decision making.
Peptide Power
The only bone graft to harness the intense biological activity of a peptide (P-15).
Ready to use
Store at room temperature. Ready to use without mixing.
Fill and forget
Don’t assume your bone graft will perform.
Tried and trusted
FDA PMA approved (2015) active biologic and has been CE Marked since 2008.
Safety by design
The unique P-15 action is surface bound and unlike growth factors only grows bone where you need it.
Attract
Attach
Activate
i-FACTOR Biologic Bone Graft novel mechanism of action enhances the body’s natural bone healing process, resulting in safe, predictable bone formation. ABM/P-15 has been in human clinical use for more than 17 years in an estimated 500,000 patients worldwide.
Learn more about the science
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